Graham Heimberg

Projects

SCimilarity: a search engine for cells

SCimilarity: a search engine for cells

Think of it as reverse image search for cells: hand the model a cell, and it returns every similar cell we've ever seen, along with the tissue, disease, and context that came with them.

From cells to patients

From cells to patients

Foundation models like SCimilarity work at the level of the single cell. But most drug-development decisions happen at the level of the patient, a very different scale of data.

Rethinking what foundation models are for

Rethinking what foundation models are for

The intuitive assumption, that highly expressed genes matter more, is often backwards. This project asked: how do you quantify a gene’s real importance to a cell?